Validation analytique LABM (XLS) - Fichier XLS

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Validation analytique LABM (XLS)

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intro
VALIDATION DE METHODE
FIDELITE : le laboratoire utilise un plan d'expérience pour réaliser une analyse de variance (ANOVA) ce qui permet de réduire la durée de non utilisation de l'automate par rapport au SH GTA 04. Cette étude permet à la fois de déterminer une variance de répétabilité mais aussi d'étudier l'influence d'un facteur (temps  lot  opérateur ...). Dans la pratique le facteur temps est étudié car il permet de vérifier aussi les divers facteurs environnementaux... L’analyse donne ainsi une variance intra-série (erreur résiduelle)  une variance inter-série (erreur factoriel) et une variance de fidélité intermédiaire  composante des erreurs factorielles et résiduelles. Les CV obtenus à partir des variances sont comparé à des CV bibliographiés. Le laboratoire s'autorise une marge au delà de la limite fixée  cette marge étant l’incertitude sur la variance pour un risque de 1%. Un test de Cochran vérifie l'homogénéité des variances et un test de Dixon* vérifie la présence de valeurs aberrantes intra-série.*Le test de Dixon peut être faussé par le faible nombre de chiffres significatifs.
JUSTESSE: le laboratoire détermine le biais ponctuel  c'est à dire la différence entre la moyenne labo et la valeur cible  généralement établi à partir du groupe des pairs ou d’une indication. Il détermine aussi l'intervalle de confiance du biais afin de vérifier si celui ci est significatif pour une risque de 5%. Entre d'autres termes  compte tenu de l’incertitude sur le résultat  le biais est lui même impacté d’une incertitude. Si l’intervalle de confiance contient la valeur zéro  alors le biais n'est pas significatif et n'est donc pas inclu dans l'incertitude de mesure. Le biais est comparé à la bibliographie (Valtec  Ricos). Le laboratoire s’autorise de valider un biais si un z-score est inférieur à 2. Il est en effet possible que les biais bibliographié ne représentent pas la réalité du terrain.
MODELE D'ETALONNAGE: ce test permet de mettre en évidence le choix du modèle d'étalonnage (linéaire  polynomial) afin de vérifier que celui ci n'a pas d'influence signifcative sur le réusltat rendu (linéarité de la réponse). Si le modèle est adapté  alors celui ci n'interfere pas significativement sur le résultat. En revanche  si un écart au modèle est observé  il faut soit réduir le domaine de mesure  soit changer de modèle. Malgrè tout  le modèle peut être accépté mais intégrera l'écart-type Sy/x dans l'incertitude de mesure.
ROBUSTESSE (approche): il s'agit d'une approche simplifiée possible grace à l'ANOVA. En effet  un test de Fisher permet de dire si la variance de répétabilité n'est pas significativement différence de la variance de fidélité intermédiaire  alors la méthode est dite "robuste".Auquel cas  elle ne l'est pas*.Il s'agit d'une approche très simple car le test s'applique à un seul facteur "temps" trop ambigu. Un plan d'expérience de type Plackett Burman ou de Taguchi est d'avantage approprié pour l'étude de la robustesse.*Le nombre de chiffres significatifs biaise fortement le résultat.
CORRELATION: le test utilise généralement une régression d'allométrie. Toutefois  si la méthode de comparaison est dite de référence  alors il faut appliquer une régression classique. Si une hétéroscédasticité est observée  il faut utiliser une régression pondérée. Un test de student vérifie l'ordonnée à l'origine et le coefficient de regression. Des intervalles de confiance à 99% sont aussi indiqués. Un diagramme des différences permet d'étudier la corrélation individuellement. Des normes de suivi (Valtec) sont déterminées avec leur incertitude de mesure (99%). Lors d'un changement de réactif  il se peut que la corrélation ne soit pas égale à 1 (réactif plus spécifique et donc nouveaux résultats plus faibles). Il faut alors s'assurer de la concordence du nouveau domaine observé avec celui spécifié dans la fiche technique. Voir exemple si dessous
INCERTITUDE DE MESURE: le modèle choisi est le suivant : u²(y) = u² (Cj) + u² (Clin) + S²r + S²f + u²(étalon). Selon les résultats obtenus  l'erreur de justesse et du modèle d'étalonnage peuvent ne pas être prises en compte dans le calcul si elles ne sont pas significatives. L'erreur de fidélité (résiduelle et factorielle) est toujours prise en compte. L'erreur totale est aussi déterminée
DOCUMENTATION / AUTRES TESTS : il s'agit de relevés bibligraphiques (fiche technique) ou de test réalisé en parallèle (ex: contamination)
PORTEE FLEXIBLE: vérifier à chaque étape de validation les critères établis
portée flexible
 B: Biologiste  S: responsable Stock  Q : Qualité  T: Technicien      
 M: Métrologue      Evolution technique
 Nouveau parametre/automate   Resp date  Nouvel automate
 1.0 Revue de contrat  B   Nouveau parametre
 1.1 Adapter la méthode aux exigences     Nouveau parametre/automate
 2.0 Achat  B/S   
 2.1 Procédure d'achat     
 3.0 Matière  B/S   
 3.1 Référencer les consommables     
 4.0 Milieux  B/M/Q   
 4.1 Condition d'utilisation analytique     
 4.2 Procédure condition de transport     
 4.3 Procédure stockage/conservation     
 5.0 Materiel  B/M   
 5.1 Mise à jour liste matériel     
 5.2 Création fiche de vie     
 5.3 Lister équipement sensible     
 5.4 Rédaction guide de maintenance     
 6.0 Main d'œuvre  B/Q/T   
 6.1 Formation technique     
 6.2 Formation réception     
 6.3 Formation préleveur     
 6.4 Création habilitation     
 7.0 Documentation  B/Q/T   
 7.1 Procédure de prélèvement     
 7.2 Procédure de réception échantillon     
 7.3 Mode opératoire automate     
 7.4 Validation analytique     
 8.0 Qualification installation  B/Q/T   
 8.1 Installation sur site     
 8.2 Document fournisseur     
 8.3 Vérification informatique     
 8.4 Sauvegarde des données     
 8.5 Paramétrage informatique     
 9.0 Qualification opérationnel  B/Q/T   
 9.1 Calibration  CQI     
 9.2 Test d'édition     
 9.3 Contrat de maintenance     
 9.4 Programme EEQ     
 10.0 Validation de méthode  B/Q/T   
 10.1 5 M     
 10.2 Tests statistiques     
 10.3 Recherche bibliographique     
 10.4 Incertitude de mesure     
 10.5 Mise en place Carte de Contrôle     
 11.0 Qualité  B/Q   
 11.1 Catalogue de préstations     
 11.2 Manuel de prélèvement     
 11.3 Ajouter technique sur compte rendu     
 11.4 Modifier avis et interprétation     
 11.5 Informer signataire     
 11.6 MAJ paramètre accrédité     
 11.7 Audit     
 11.8 Imprimer document qualité modifié     
données 1
                   OBJECTIFS ANALYTIQUES : ETAT DE L'ART SFBC                        
                    Unités Niveaux        Répétabilité ( % )   Reproductibilité ( % )   Justesse ( % )   Normes de Suivi   Norme d'interprétation  
Valtec bas normal élevé bas normal élevé bas normal élevé bas normal élevé bas normal élevé bas normal élevé   Bas Moyen Elevé Anc  U Conv Bas Moyen Elevé Bas Moyen Elevé Bas Moyen Elevé Bas Moyen Elevé Bas Moyen Elevé Bas Moyen Elevé
unité niveau   CVr   Cvfi   biais %   Norme de suivi   ET Ricos   SUBSTRATS                        
                   Acide urique µmol/l 150.0 300.0 450.0 mg/l x 0.168 25.200000000000003 50.400000000000006 75.60000000000001 2.7 2.4 2.1 3.6 3.2 2.8 7.1 6.2 5.3 23.0 41.0 53.0 14.0 12.3333333333333 10.666666666666666
g/l x 0.36 1.08 2.88 2.4 1.8 1.2 3.2 2.4 1.6 5.1 4.4 3.7 0.3 0.6 1.1 10.0 8.333333333333334 7.5 Ammonium µmol/l 50.0 100.0 200.0      5.3 4.5 3.8 7.0 6.0 5.0 7.1 6.7 6.2 15.0 25.0 42.0 14.0 13.0 12.5
                   CO2 mmol/l 10.0 20.0 30.0      7.5 6.0 4.5 10.0 8.0 6.0 6.6 6.0 5.3 4.2 6.8 7.6 13.0 12.0 10.666666666666666
                   Bilirubine Totale µmol/l 15.0 50.0 150.0 mg/l x 0.585 8.774999999999999 29.25 87.75 5.1 4.2 3.2 6.8 5.6 4.2 13.4 10.6 11.2 4.3 11.9 26.7 26.666666666666668 21.2 22.46666666666667
                   Calcium ionisé mmol/l 0.6 1.0 1.5      1.2 1.2 1.2 1.6 1.6 1.6 1.7 1.7 1.7 0.04 0.07 0.1 5.0 5.0 4.666666666666667
                   Calcium total mmol/l 1.8 2.4 3.4 mg/l x 40.0 72.0 96.0 136.0 1.2 1.2 1.2 1.6 1.6 1.6 1.7 1.7 1.7 0.12 0.16 0.23 3.333333333333333 3.3333333333333335 3.235294117647059
                   Chlore mmol/l 80.0 105.0 120.0      1.2 1.2 1.2 1.6 1.6 1.6 1.9 1.9 1.9 5.4 7.1 8.1 3.875 3.8095238095238093 3.833333333333333
                   Cholesterol mmol/l 3.0 5.0 8.0 g/l x 0.387 1.161 1.935 3.096 3.0 3.0 3.0 4.0 4.0 4.0 5.7 5.7 5.7 0.51 0.85 1.36 11.333333333333334 11.399999999999999 11.5
                   HDL mmol/l 0.8 1.4 2.2 g/l x 0.387 0.30960000000000004 0.5418 0.8514 4.5 4.5 4.5 6.0 6.0 6.0 8.0 8.0 8.0 0.2 0.36 0.56 16.25 15.714285714285715 15.909090909090908
                   Creatinine µmol/l 50.0 140.0 590.0 mg/l x 0.113 5.65 15.82 66.67 4.5 3.4 1.8 6.0 4.5 2.4 8.0 7.8 7.6 13.0 27.0 60.0 16.0 15.714285714285714 15.254237288135593
                   Fer µmol/l 5.0 20.0 40.0 ug/dl x 5.6 28.0 112.0 224.0 6.0 3.8 3.0 8.0 5.0 4.0 12.7 8.7 6.9 1.7 4.2 6.8 26.0 17.5 13.75
                   Ferritine µg/l 20.0 200.0 800.0      7.5 6.0 6.0 10.0 8.0 8.0 8.3 6.0 6.0 8.5 68.0 272.0 16.5 12.0 12.0
                   Folates µg/l 1.0 4.0 15.0      7.5 6.0 6.0 10.0 8.0 8.0 11.0 8.9 8.9 0.42 1.35 5.0 30.0 17.5 18.0
                   Fructosamine µmol/l 200.0 400.0 600.0      3.8 3.8 3.8 5.0 5.0 5.0 8.7 7.5 6.2 42.0 85.0 127.0 17.5 15.0 12.5
                   Glucose mmol/l 2.0 6.0 16.0 g/l x 0.18 0.36 1.08 2.88 2.4 1.8 1.2 3.2 2.4 1.6 5.1 4.4 3.7 0.3 0.6 1.1 10.0 8.333333333333334 7.5
RICOS                   HbA1c % 4.0 7.0 10.0      3.8 3.8 3.8 5.0 5.0 5.0 6.2 6.2 6.2 0.8 1.5 2.1 12.5 12.857142857142858 12.0
                   Lactate mmol/l 1.0 3.0 8.0      3.8 3.8 3.8 5.0 5.0 5.0 8.7 8.7 8.7 0.21 0.64 1.7 17.0 17.333333333333332 17.375
                   Magnesium mmol/l 0.5 0.9 1.6 mg/l x 24.3 12.15 21.87 38.88 3.0 2.4 2.4 4.0 3.2 3.2 4.5 5.1 5.1 0.08 0.12 0.22 8.0 10.0 10.0
                   Phosphate mmol/l 0.5 1.5 3.0 mg/l x 31.0 15.5 46.5 93.0 3.0 2.5 1.8 4.0 3.3 2.4 3.9 4.5 5.1 0.08 0.21 0.31 8.0 9.333333333333334 10.0
                   Potassium mmol/l 2.0 4.0 6.0      1.5 1.2 1.2 2.0 1.6 1.6 2.9 3.1 3.1 0.17 0.27 0.41 5.5 6.25 6.166666666666667
                   Protéines totales g/l 40.0 65.0 90.0      2.4 1.8 1.8 3.2 2.4 2.4 3.8 3.8 3.2 5.4 6.6 9.2 7.75 7.538461538461539 6.444444444444445
                   Sodium mmol/l 120.0 140.0 160.0      1.0 0.8 0.7 1.3 1.1 0.9 1.5 1.4 1.3 6.6 6.5 6.1 3.0 2.857142857142857 2.625
                   Triglycérides mmol/l 0.5 1.5 3.0 g/l x 0.875 0.4375 1.3125 2.625 4.2 3.6 3.6 5.6 4.8 4.8 8.3 6.4 6.4 0.12 0.31 0.61 16.0 12.666666666666666 12.666666666666666
                   Urée mmol/l 2.5 10.0 25.0 g/l x 0.06 0.15 0.6 1.5 4.5 3.0 1.9 6.0 4.0 2.5 10.4 6.9 4.3 0.6 1.7 2.7 20.0 14.0 8.8
                   SUBSTRATS URINAIRES                        
                   Acide urique U mmol/l 0.5 1.5 4.0 g/l x 0.168 0.084 0.252 0.672 4.5 3.8 3.0 6.0 5.0 4.0 10.4 8.7 6.9 0.1 0.3 0.7 20.0 20.0 15.0
                   Calcium U mmol/l 1.0 2.5 4.0 mg/l x 40.0 40.0 100.0 160.0 3.0 3.0 3.0 4.0 4.0 4.0 10.0 10.0 10.0 0.2 0.4 0.7 20.0 20.0 20.0
                   Chlore U mmol/l 30.0 80.0 140.0      3.8 3.0 2.3 5.0 4.0 3.0 8.7 4.5 4.0 6.0 14.0 18.0 16.666666666666668 8.75 7.857142857142857
                   Créatinine U mmol/l 1.0 8.0 20.0 g/l x 0.113 0.113 0.904 2.2600000000000002 4.5 3.8 3.8 6.0 5.0 5.0 8.0 6.2 6.2 0.0 2.0 4.0 0.0 12.5 15.0
                   Glucose U mmol/l 1.0 10.0 30.0 g/l x 0.18 0.18 1.7999999999999998 5.3999999999999995 4.5 3.8 3.8 6.0 5.0 5.0 5.3 4.9 6.2 0.3 2.1 6.4 10.0 10.0 12.333333333333334
                   Magnesium U mmol/l 0.5 2.0 6.0 mg/l x 24.3 12.15 48.6 145.8 4.5 4.5 4.5 6.0 6.0 6.0 8.0 8.0 8.0 0.1 0.5 1.5 20.0 15.0 16.666666666666668
                   MicroAlb U mg/l 20.0 50.0 100.0      6.0 4.5 4.5 8.0 6.0 6.0 8.9 8.0 8.0 7.0 13.0 26.0 20.0 16.0 16.0
                   Phosphate U mmol/l 2.0 10.0 20.0 mg/l x 31.0 62.0 310.0 620.0 4.5 4.5 3.8 6.0 6.0 5.0 10.4 8.0 6.2 0.5 2.6 4.2 20.0 16.0 12.5
                   Potassium U mmol/l 20.0 100.0 200.0      3.8 3.8 3.0 5.0 5.0 4.0 4.9 4.9 4.5 4.0 21.0 34.0 10.0 10.0 9.0
                   Protéines U g/l 0.2 0.6 1.2      6.8 5.3 3.8 9.0 7.0 5.0 17.9 13.3 8.7 0.08 0.18 0.25 35.0 26.666666666666668 17.5
                   Sodium U mmol/l 20.0 100.0 200.0      3.8 3.8 3.0 5.0 5.0 4.0 4.9 4.9 4.5 4.0 21.0 34.0 10.0 10.0 9.0
                   Urée U mmol/l 10.0 150.0 350.0 g/l x 0.06 0.6 9.0 21.0 4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 3.0 38.0 74.0 20.0 13.333333333333334 12.571428571428571
                   ENZYMES                        
                   5'Nu U/l 10.0 20.0 50.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 3.0 5.0 11.0 20.0 15.0 12.0
                   a-Amylase U/l 50.0 150.0 400.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 13.0 38.0 85.0 16.0 13.333333333333334 12.5
                   ALAT U/l 20.0 50.0 200.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 5.0 13.0 42.0 15.0 14.0 12.5
                   ASAT U/l 20.0 50.0 200.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 5.0 13.0 42.0 15.0 14.0 12.5
                   CK U/l 50.0 100.0 400.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 13.0 26.0 85.0 16.0 13.0 12.5
                   GGT U/l 20.0 50.0 390.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 5.0 13.0 83.0 15.0 14.0 12.564102564102564
                   LDH U/l 150.0 300.0 900.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 38.0 76.0 191.0 16.0 13.333333333333334 12.444444444444445
                   Lipase U/l 80.0 200.0 400.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 20.0 51.0 85.0 16.25 13.5 12.5
                   PAL U/l 20.0 50.0 390.0      4.5 4.5 3.8 6.0 6.0 5.0 8.0 6.7 6.2 5.0 13.0 83.0 15.0 14.0 12.564102564102564
                   PROTEINES SPECIFIQUES                        
                   a1AT g/l 1.0 2.0 4.0      4.5 4.5 3.8 6.0 6.0 5.0 10.4 10.4 8.7 0.25 0.51 0.85 21.0 21.0 17.25
                   a2-Macroglobuline g/l 1.0 2.0 4.0      4.5 3.8 3.0 6.0 5.0 4.0 5.3 6.2 6.9 0.25 0.42 0.68 11.0 12.5 13.750000000000002
                   Albumine g/l 20.0 30.0 50.0      4.5 3.8 3.0 6.0 5.0 4.0 5.3 6.2 6.9 5.1 6.4 8.5 10.5 12.333333333333334 13.8
                   ApoA1 g/l 0.5 1.5 2.0      6.0 4.5 3.8 8.0 6.0 5.0 12.7 10.4 10.9 0.2 0.4 0.4 20.0 20.0 20.0
                   ApoB g/l 0.5 1.5 2.5      6.8 5.3 4.5 9.0 7.0 6.0 12.0 9.7 10.4 0.19 0.45 0.64 24.0 19.333333333333332 20.8
                   b2-Microglobuline mg/l 2.0 10.0 25.0      6.0 5.3 5.3 8.0 7.0 7.0 8.9 7.1 7.1 0.68 2.97 7.42 18.0 14.3 14.28
                   Céruléoplasmine g/l 0.2 0.4 0.8      6.0 4.5 3.8 8.0 6.0 5.0 8.9 8.0 6.2 0.07 0.1 0.17 20.0 15.0 12.5
                   C3 g/l 0.5 1.0 3.0      6.0 4.5 3.8 8.0 6.0 5.0 6.0 8.0 8.7 0.2 0.3 0.6 20.0 20.0 16.666666666666668
                   C4 g/l 0.2 0.3 0.6      6.0 4.5 3.8 8.0 6.0 5.0 6.0 8.0 8.7 0.05 0.08 0.13 10.0 16.666666666666668 16.666666666666668
                   CRP mg/l 15.0 50.0 100.0      9.0 4.5 3.8 12.0 6.0 5.0 9.0 8.0 7.5 7.6 12.7 21.2 18.0 16.0 15.0
                   Haptoglobine g/l 0.5 1.5 3.0      4.5 3.8 3.0 6.0 5.0 4.0 10.4 8.7 6.9 0.13 0.32 0.51 20.0 17.333333333333332 14.0
                   IgA g/l 1.0 2.0 4.0      4.5 3.8 3.0 6.0 5.0 4.0 8.0 7.5 6.9 0.3 0.4 0.7 20.0 15.0 15.0
                   IgE kUI/l 20.0 200.0 500.0      9.0 6.0 6.0 12.0 8.0 8.0 9.0 6.0 6.0 10.0 68.0 170.0 20.0 12.0 12.0
                   IgG g/l 5.0 10.0 20.0      4.5 3.8 3.0 6.0 5.0 4.0 10.4 8.7 6.9 1.27 2.12 3.39 20.8 17.3 13.85
                   IgM g/l 1.0 2.0 4.0      4.5 3.8 3.0 6.0 5.0 4.0 8.0 7.5 6.9 0.3 0.4 0.7 20.0 15.0 15.0
                   Oroso g/l 0.4 0.8 1.6      5.3 4.5 3.8 7.0 6.0 5.0 8.5 8.0 7.5 0.1 0.2 0.3 25.0 12.5 12.5
                   PréAlb g/l 0.2 0.3 0.6      6.0 4.5 3.8 8.0 6.0 5.0 8.9 8.0 7.5 0.1 0.1 0.1 50.0 33.333333333333336 16.666666666666668
                   Transférrine g/l 1.0 2.0 4.0      6.0 4.5 3.8 8.0 6.0 5.0 8.9 8.6 7.5 0.34 0.51 0.85 18.0 17.0 15.0
                   GAZ DU SANG                        
                   HbCO % 5.0 10.0 15.0      7.5 3.8 3.8 10.0 5.0 5.0 17.3 14.1 8.7 2.12 2.12 3.18 34.6 28.3 17.333333333333332
                   HbO2 % 40.0 70.0 100.0      3.8 3.8 3.8 5.0 5.0 5.0 8.7 8.7 8.7 8.5 14.8 21.2 17.25 17.285714285714285 17.3
                   metHb % 0.1 1.5 4.5      18.8 11.3 7.5 25.0 15.0 10.0 16.6 20.0 11.2 0.1 1.0 1.9 500.0 40.0 22.22222222222222
                   pCO2 mmHg 20.0 40.0 100.0      4.5 3.8 3.8 6.0 5.0 5.0 8.0 6.2 6.2 5.1 8.5 21.2 16.0 12.5 12.5
                   pH (unité) unité 7.2 7.4 7.55                  0.0 0.0 0.0
                   pH (nmol/l) nmol/l 63.1 39.8 28.2      1.5 1.5 1.5 2.0 2.0 2.0 3.5 3.5 3.5 5.35 3.38 2.39 6.925515055467511 6.934673366834171 6.914893617021277
                   p02 mmHg 20.0 80.0 200.0      1.5 1.5 1.5 2.0 2.0 2.0 9.8 7.7 7.7 1.7 6.8 17.0 19.5 15.5 15.5
                   MEDICAMENTS                        
                   Acide Valproïque mg/l 30.0 80.0 130.0      7.5 4.0 5.0 10.0 8.0 8.0 11.2 8.9 8.9 12.7 27.2 44.1 22.333333333333332 17.875 17.923076923076923
                   Amikacine mg/l 2.0 20.0 40.0      7.5 6.0 6.0 10.0 8.0 8.0 11.2 8.9 8.9 0.8 6.8 13.6 20.0 18.0 18.0
                   Carbamazépine mg/l 3.0 10.0 15.0      7.5 5.3 5.3 10.0 7.0 7.0 11.2 9.7 13.3 1.3 3.0 4.5 23.333333333333332 19.0 26.666666666666668
                   Digoxine µg/l 0.5 1.5 3.0      9.0 5.3 5.3 12.0 7.0 7.0 9.0 12.1 12.1 0.3 0.5 0.9 20.0 26.666666666666668 23.333333333333332
                   Gentamicine mg/l 2.0 5.0 10.0      7.5 6.0 6.0 10.0 8.0 8.0 11.2 12.7 12.7 0.8 1.7 3.4 20.0 26.0 25.0
                   Lithium mmol/l 0.2 0.6 1.2      7.5 3.8 3.8 10.0 5.0 5.0 11.2 6.2 6.2 0.08 0.13 0.25 20.0 11.666666666666668 12.5
                   Méthotrexate mmol/l 0.2 10.0 20.0      11.3 7.5 7.5 15.0 10.0 10.0 20.0 11.2 11.2 0.1 4.2 8.5 50.0 22.000000000000004 22.5
                   Paracétamol mg/l 12.0 40.0 150.0      6.0 4.5 4.5 8.0 6.0 6.0 12.7 10.4 10.4 4.1 10.2 38.2 25.0 20.750000000000004 20.8
                   Phénobarbital mg/l 10.0 25.0 50.0      7.5 5.3 5.3 10.0 7.0 7.0 11.2 13.3 13.3 4.2 7.4 14.8 22.000000000000004 26.4 26.6
                   Phénytoïne mg/l 1.0 15.0 25.0      9.0 6.0 6.0 12.0 8.0 8.0 9.0 8.9 8.9 0.51 5.09 8.49 18.0 17.866666666666667 17.88
                   Salycilates mg/l 40.0 150.0 400.0      6.0 5.3 4.5 8.0 7.0 6.0 12.7 8.5 8.0 13.6 44.5 101.8 25.499999999999996 17.0 16.0
                   Théophiline mg/l 5.0 15.0 30.0      7.5 7.5 7.5 10.0 10.0 10.0 11.2 6.6 6.6 2.1 6.4 12.7 22.000000000000004 13.333333333333334 13.333333333333334
                   Vancomycine mg/l 10.0 30.0 70.0      7.5 6.0 6.0 10.0 8.0 8.0 11.2 8.9 8.9 4.24 10.18 23.76 22.400000000000002 17.9 17.885714285714286
                   MARQUEURS TUMORAUX                        
                   ACE ng/ml 5.0 15.0 50.0      11.3 6.0 6.0 15.0 8.0 8.0 13.2 8.9 8.9 3.2 5.1 17.0 26.0 18.0 17.8
                   AFP kUI/l 10.0 50.0 200.0      11.3 6.0 6.0 15.0 8.0 8.0 13.2 8.0 8.9 6.4 17.0 67.9 26.0 17.8 17.9
                   CA125 kU/l 20.0 40.0 100.0      6.8 5.3 5.3 9.0 7.0 7.0 17.9 12.1 9.7 7.6 11.9 29.7 35.5 24.249999999999996 19.5
                   CA15-3 kU/l 20.0 40.0 100.0      6.8 5.3 5.3 9.0 7.0 7.0 17.9 12.1 9.7 7.6 11.9 29.7 35.5 24.249999999999996 19.5
                   CA19-9 kU/l 20.0 40.0 150.0      9.0 7.5 7.5 12.0 10.0 10.0 21.9 11.2 11.2 10.2 17.0 63.6 44.00000000000001 22.25 22.333333333333332
                   PSA ng/ml 0.5 5.0 50.0      15.0 5.3 5.3 20.0 7.0 7.0 22.4 13.3 13.3 0.42 1.48 14.8 44.0 26.6 26.6
                   HORMONES                        
                   Cortisol nmol/l 100.0 500.0 1000.0      11.3 7.5 7.5 15.0 10.0 10.0 13.2 11.2 11.2 64.0 212.0 424.0 26.0 22.4 22.4
                   E2 pmol/l 100.0 1000.0 10000.0      18.8 7.5 7.5 25.0 10.0 10.0 24.5 11.2 11.2 106.0 424.0 4243.0 49.0 22.4 22.36
                   FSH UI/l 2.0 20.0 50.0      7.5 6.0 6.0 10.0 8.0 8.0 17.3 12.7 12.7 0.8 10.8 17.0 35.0 25.499999999999996 25.4
                   GH mUI/l 5.0 20.0 50.0      7.5 4.5 4.5 10.0 6.0 6.0 11.2 10.4 10.4 2.1 5.1 12.7 22.000000000000004 21.0 20.8
                   HCG B UI/l 2.0 100.0 900.0      11.3 7.5 7.5 15.0 10.0 10.0 26.0 11.2 11.2 1.3 42.0 382.0 50.0 22.0 22.333333333333332
                   Insuline mUI/l 10.0 50.0 100.0      7.5 6.0 6.0 10.0 8.0 8.0 17.3 12.7 12.7 4.2 17.0 33.9 35.0 25.4 25.4
                   LH UI/l 5.0 20.0 50.0      7.5 6.0 6.0 10.0 8.0 8.0 17.3 12.7 12.7 2.1 6.8 17.0 34.0 25.499999999999996 25.4
                   PTH ng/l 15.0 70.0 250.0      11.3 6.0 6.0 15.0 8.0 8.0 20.0 12.7 12.7 9.5 23.8 84.9 40.0 25.428571428571427 25.36
                   Peptide C nmol/l 0.5 1.5 3.0      11.3 6.0 6.0 15.0 8.0 8.0 20.0 12.7 12.7 0.32 0.51 1.02 40.0 25.333333333333332 25.333333333333332
                   Progesterone nmol/l 3.0 20.0 70.0      18.8 7.5 7.5 25.0 10.0 10.0 24.5 11.2 11.2 3.2 8.0 30.0 50.0 20.0 22.857142857142858
                   Prolactine nmol/l 150.0 600.0 1500.0      11.3 7.5 7.5 15.0 10.0 10.0 20.0 11.2 11.2 95.0 255.0 636.0 40.0 22.333333333333332 22.333333333333332
                   FT3 pmol/l 3.0 7.0 15.0      8.3 6.0 6.0 11.0 8.0 8.0 16.7 12.7 12.7 1.4 2.4 5.1 33.333333333333336 25.714285714285715 25.333333333333332
                   FT4 pmol/l 10.0 17.0 25.0      7.5 6.0 6.0 10.0 8.0 8.0 17.3 12.7 12.7 4.2 5.8 8.5 35.0 25.294117647058822 25.2
                   Testosterone nmol/l 2.0 5.0 30.0      18.8 7.5 7.5 25.0 10.0 10.0 16.6 11.2 11.2 2.1 6.4 12.7 35.0 68.0 22.333333333333332
                   TSH mUI/l 0.1 1.0 30.0      15.0 5.3 3.8 20.0 7.0 5.0 28.7 13.3 8.7 0.1 0.3 6.4 100.0 30.0 17.333333333333332
                   RICOS Unités Niveaux        Répétabilité ( % )   Reproductibilité ( % )   Justesse ( % )      Erreur totale  
                             Bas Moyen Elevé Bas Moyen Elevé Bas Moyen Elevé    Bas Moyen Elevé
                   Sang-plasma                        
                   11-Desoxycortisol S          2.0112781954887216 8.045112781954886 6.033834586466164 2.675 10.7 8.024999999999999 4.753189718494308 9.5 14.259569155482925    9.140189718494309 27.048 27.420569155482923
                   17-Hydroxyprogesterone          1.8421052631578947 7.368421052631579 5.526315789473684 2.45 9.8 7.3500000000000005 6.993210993527938 14.0 20.979632980583812    11.011210993527937 30.072 33.03363298058381
                   5' Nucleotidase          1.0714285714285714 4.285714285714286 3.2142857142857144 1.425 5.7 4.275 2.1156042281107306 4.2 6.346812684332192    4.45260422811073 13.547999999999998 13.357812684332192
                   a1-Acid Glycoprotein          1.0714285714285714 4.285714285714286 3.2142857142857144 1.425 5.7 4.275 3.4180129461428317 6.8 10.254038838428496    5.755012946142831 16.148 17.265038838428495
                   a1-Antichymotrypsin          1.2781954887218043 5.112781954887217 3.834586466165413 1.7 6.8 5.1 2.8425890487370844 5.7 8.527767146211254    5.630589048737084 16.852 16.89176714621125
                   a1-Antitrypsin          0.5639097744360902 2.255639097744361 1.6917293233082706 0.75 3.0 2.25 2.1668669779199643 4.3 6.500600933759893    3.3968669779199643 9.219999999999999 10.190600933759892
                   a1-Globulin          1.0714285714285714 4.285714285714286 3.2142857142857144 1.425 5.7 4.275 3.164055941351227 6.3 9.49216782405368    5.501055941351227 15.648 16.50316782405368
                   a2-Antiplasmin          0.5827067669172932 2.3308270676691727 1.7481203007518797 0.775 3.1 2.325 x x x    x x x
                   a2-Globulins          0.9774436090225563 3.9097744360902253 2.9323308270676693 1.3 5.2 3.9000000000000004 2.0439697894049216 4.1 6.131909368214765    4.175969789404922 12.628 12.527909368214765
                   a2-Macroglobulin          0.3195488721804511 1.2781954887218043 0.9586466165413533 0.425 1.7 1.275 2.3758222260935264 4.8 7.127466678280579    3.0728222260935265 7.587999999999999 9.21846667828058
                   a-Amylase (ricos)          0.8270676691729324 3.3082706766917296 2.481203007518797 1.1 4.4 3.3000000000000003 3.700886718071765 7.4 11.102660154215295    5.504886718071765 14.616 16.514660154215296
                   a-Amylase (pancreatic)          1.1090225563909775 4.43609022556391 3.3270676691729326 1.475 5.9 4.425000000000001 4.0134539364492525 8.0 12.040361809347758    6.432453936449253 17.676000000000002 19.29736180934776
                   a-Carotene          3.364661654135338 13.458646616541351 10.093984962406013 4.475 17.9 13.424999999999999 9.275842279814809 18.6 27.827526839444424    16.61484227981481 47.955999999999996 49.84452683944442
                   a-Fetoprotein(non hepatic carcinoma)          1.1278195488721805 4.511278195488722 3.3834586466165413 1.5 6.0 4.5 5.942432162002357 11.9 17.82729648600707    8.402432162002356 21.740000000000002 25.20729648600707
                   a-Tocopherol          1.2969924812030076 5.18796992481203 3.8909774436090228 1.725 6.9 5.175000000000001 2.5477931627194543 5.1 7.643379488158363    5.376793162719455 16.416 16.13037948815836
                   Acid phosphatase          0.8458646616541353 3.3834586466165413 2.537593984962406 1.125 4.5 3.375 1.4958797578682586 3.0 4.487639273604776    3.3408797578682585 10.379999999999999 10.022639273604774
                   Acid phosphatase tartrate-resistant (TR-ACP)          0.7518796992481203 3.007518796992481 2.255639097744361 1.0 4.0 3.0 1.940078928806764 3.9 5.820236786420292    3.580078928806764 10.459999999999999 10.740236786420292
                   Acid phosphatase prostatic activity (PAP)          3.176691729323308 12.706766917293232 9.530075187969924 4.225 16.9 12.674999999999999 x x x    x x x
                   Activated partial thromboplastine time          0.2631578947368421 1.0526315789473684 0.7894736842105261 0.35 1.4 1.0499999999999998 1.1267347735824966 2.3 3.38020432074749    1.7007347735824965 4.596 5.102204320747489
                   Acyl/free carnitine          0.9774436090225563 3.9097744360902253 2.9323308270676693 1.3 5.2 3.9000000000000004 3.675106290979895 7.3 11.025318872939685    5.807106290979895 15.828 17.421318872939686
                   Adiponectin          1.7669172932330828 7.067669172932331 5.3007518796992485 2.35 9.4 7.050000000000001 6.817807565486137 13.6 20.45342269645841    10.671807565486137 29.016 32.015422696458415
                   Adenosine deaminase (ADA)          1.1090225563909775 4.43609022556391 3.3270676691729326 1.475 5.9 4.425000000000001 3.5070019247214566 7.0 10.521005774164369    5.926001924721456 16.676000000000002 17.77800577416437
                   Alanine aminopeptidase          0.39473684210526316 1.5789473684210527 1.1842105263157896 0.525 2.1 1.5750000000000002 x x x    x x x
                   Alanine aminotransferase          2.2932330827067666 9.172932330827066 6.879699248120299 3.05 12.2 9.149999999999999 6.022159600176668 12.0 18.066478800530003    11.024159600176667 32.007999999999996 33.07247880053
                   Albumin          0.3007518796992481 1.2030075187969924 0.9022556390977444 0.4 1.6 1.2000000000000002 0.6525191568069094 1.3 1.9575574704207281    1.3085191568069094 3.9240000000000004 3.9255574704207286
                   Aldosterone          2.763157894736842 11.052631578947368 8.289473684210526 3.675 14.7 11.024999999999999 6.215366541886327 12.4 18.646099625658984    12.242366541886327 36.507999999999996 36.72709962565898
                   Alkaline phosphatase          0.6015037593984962 2.406015037593985 1.8045112781954888 0.8 3.2 2.4000000000000004 3.2015621187164247 6.4 9.604686356149275    4.5135621187164245 11.648 13.540686356149275
                   Alkaline phosphatase  bone          0.5827067669172932 2.3308270676691727 1.7481203007518797 0.775 3.1 2.325 4.516981846321723 9.0 13.55094553896517    5.787981846321723 14.084 17.36394553896517
                   Alkaline phosphatase  liver          0.9398496240601504 3.7593984962406015 2.819548872180451 1.25 5.0 3.75 3.599045012221992 7.2 10.797135036665976    5.6490450122219915 15.399999999999999 16.947135036665976
                   Alkaline phosphatase  placental          1.8045112781954886 7.2180451127819545 5.413533834586465 2.4 9.6 7.199999999999999 x x x    x x x
                   Amyloid A          2.3496240601503757 9.398496240601503 7.048872180451127 3.125 12.5 9.375 8.240524861924754 16.5 24.721574585774263    13.365524861924754 37.0 40.09657458577426
                   Androstendione          1.0526315789473684 4.2105263157894735 3.1578947368421044 1.4 5.6 4.199999999999999 6.536460242363599 13.1 19.609380727090798    8.832460242363599 22.284 26.497380727090796
                   Androstenedione          1.0902255639097744 4.360902255639098 3.270676691729323 1.45 5.8 4.35 6.536460242363599 13.1 19.609380727090798    8.9144602423636 22.612 26.743380727090795
                   Angiotensin converting enzyme          0.018796992481203006 0.07518796992481203 0.056390977443609026 0.025 0.1 0.07500000000000001 x x x    x x x
                   Antithrombin III          0.48872180451127817 1.9548872180451127 1.4661654135338347 0.65 2.6 1.9500000000000002 2.019939664940515 4.0 6.059818994821545    3.085939664940515 8.264 9.257818994821545
                   Apolipoprotein A1          0.6203007518796991 2.4812030075187965 1.8609022556390973 0.825 3.3 2.4749999999999996 1.861660884801526 3.7 5.584982654404578    3.2146608848015257 9.111999999999998 9.643982654404578
                   Apolipoprotein B          0.6578947368421052 2.631578947368421 1.9736842105263157 0.875 3.5 2.625 2.9776511296657975 6.0 8.932953388997392    4.4126511296657975 11.739999999999998 13.237953388997392
                   Ascorbic Acid          2.443609022556391 9.774436090225564 7.330827067669173 3.25 13.0 9.75 5.057482081035977 10.1 15.172446243107931    10.387482081035976 31.42 31.16244624310793
                   Aspartate aminotransferase          1.1278195488721805 4.511278195488722 3.3834586466165413 1.5 6.0 4.5 2.686831312159362 5.4 8.060493936478085    5.146831312159362 15.24 15.440493936478084
                   b-2-Microglobulin          0.5639097744360902 2.255639097744361 1.6917293233082706 0.75 3.0 2.25 2.073116615147349 4.1 6.219349845442046    3.303116615147349 9.02 9.909349845442046
                   Basophile  count          2.631578947368421 10.526315789473683 7.894736842105263 3.5 14.0 10.5 7.692366345930229 15.4 23.07709903779069    13.432366345930228 38.36 40.29709903779069
                   b-Carotene          3.3834586466165413 13.533834586466165 10.150375939849624 4.5 18.0 13.5 6.698985464232625 13.4 20.096956392697876    14.078985464232625 42.92 42.23695639269788
                   b-Cryptoxantin          3.458646616541353 13.834586466165412 10.375939849624059 4.6 18.4 13.799999999999999 x x x    x x x
                   b-Globulins          0.9586466165413533 3.834586466165413 2.87593984962406 1.275 5.1 3.8249999999999997 1.6993564958536511 3.4 5.098069487560953    3.7903564958536506 11.764 11.371069487560952
                   Bilirubin total          2.236842105263158 8.947368421052632 6.7105263157894735 2.975 11.9 8.925 5.71106382384228 11.4 17.13319147152684    10.590063823842279 30.915999999999997 31.77019147152684
                   Bilirubin conjugated          3.458646616541353 13.834586466165412 10.375939849624059 4.6 18.4 13.799999999999999 7.093659140387279 14.2 21.280977421161836    14.637659140387278 44.37599999999999 43.912977421161834
                   CA 125 antigen          2.3308270676691727 9.32330827067669 6.992481203007519 3.1 12.4 9.3 7.4908798715504705 15.0 22.472639614651413    12.57487987155047 35.336 37.724639614651416
                   CA 15 3 antigen          0.5827067669172932 2.3308270676691727 1.7481203007518797 0.775 3.1 2.325 7.899386843293598 15.8 23.698160529880795    9.170386843293599 20.884 27.511160529880794
                   CA 19 9 antigen          1.5037593984962405 6.015037593984962 4.511278195488722 2.0 8.0 6.0 12.905909499140307 25.8 38.71772849742092    16.18590949914031 38.92 48.557728497420925
                   CA 549 antigen          0.8646616541353382 3.458646616541353 2.5939849624060147 1.15 4.6 3.4499999999999997 4.327185141636535 8.7 12.981555424909605    6.213185141636535 16.244 18.639555424909602
                   Calcium          0.18796992481203006 0.7518796992481203 0.5639097744360902 0.25 1.0 0.75 0.42297310789221576 0.8 1.2689193236766472    0.8329731078922158 2.44 2.498919323676647
                   Carbohydrate deficient transferrin          0.6766917293233082 2.706766917293233 2.030075187969925 0.9 3.6 2.7 4.918237743338564 9.8 14.75471323001569    6.3942377433385635 15.704 19.18271323001569
                   Carcinoembryonic antigen (CEA)          1.2030075187969924 4.81203007518797 3.6090225563909777 1.6 6.4 4.800000000000001 7.129001069574895 14.3 21.387003208724686    9.753001069574895 24.796 29.259003208724685
                   CD4 lymphocyte count          2.3496240601503757 9.398496240601503 7.048872180451127 3.125 12.5 9.375 x x x    x x x
                   Ceruloplasmin          0.5451127819548872 2.180451127819549 1.6353383458646615 0.725 2.9 2.175 1.5654971255163646 3.1 4.696491376549094    2.754497125516364 7.856 8.263491376549094
                   Chloride          0.11278195488721804 0.45112781954887216 0.33834586466165406 0.15 0.6 0.44999999999999996 0.24011715890373184 0.5 0.7203514767111955    0.4861171589037318 1.484 1.4583514767111954
                   Cholesterol (ricos)          0.5075187969924813 2.030075187969925 1.5225563909774438 0.675 2.7 2.0250000000000004 2.016339505142921 4.0 6.049018515428763    3.123339505142921 8.428 9.370018515428763
                   Cholinesterase          0.6578947368421052 2.631578947368421 1.9736842105263157 0.875 3.5 2.625 1.567043394421482 3.1 4.701130183264446    3.0020433944214817 8.84 9.006130183264446
                   Cholinesterase  activity          0.5075187969924813 2.030075187969925 1.5225563909774438 0.675 2.7 2.0250000000000004 1.453712918701626 2.9 4.361138756104878    2.560712918701626 7.327999999999999 7.682138756104878
                   Cholinesterase  immunoreactive          0.6015037593984962 2.406015037593985 1.8045112781954888 0.8 3.2 2.4000000000000004 x x x    x x x
                   C3 complement          0.48872180451127817 1.9548872180451127 1.4661654135338347 0.65 2.6 1.9500000000000002 2.0554804791094465 4.1 6.16644143732834    3.1214804791094464 8.364 9.36444143732834
                   C4 complement          0.8458646616541353 3.3834586466165413 2.537593984962406 1.125 4.5 3.375 4.320680646611133 8.6 12.962041939833398    6.165680646611133 15.98 18.497041939833398
                   Chromogranin A          1.2030075187969924 4.81203007518797 3.6090225563909777 1.6 6.4 4.800000000000001 3.6561805548960518 7.3 10.968541664688155    6.280180554896052 17.796 18.840541664688157
                   Copper          0.7518796992481203 3.007518796992481 2.255639097744361 1.0 4.0 3.0 2.576941016011038 5.2 7.730823048033114    4.216941016011038 11.76 12.650823048033114
                   Copper          0.4699248120300752 1.8796992481203008 1.4097744360902256 0.625 2.5 1.875 1.8069743357336316 3.6 5.420923007200895    2.8319743357336318 7.699999999999999 8.495923007200895
                   Cortisol (ricos)          1.9736842105263157 7.894736842105263 5.921052631578947 2.625 10.5 7.875 6.270179921660941 12.5 18.810539764982824    10.57517992166094 29.72 31.725539764982823
                   C Peptide          1.5601503759398496 6.2406015037593985 4.680451127819549 2.075 8.3 6.2250000000000005 3.565897502733358 7.1 10.697692508200074    6.968897502733358 20.712 20.906692508200074
                   C-Propeptide type I procollagen          0.7706766917293232 3.0827067669172927 2.3120300751879697 1.025 4.1 3.0749999999999997 2.42706097986845 4.9 7.281182939605349    4.1080609798684495 11.623999999999999 12.324182939605349
                   C-Reactive protein          3.9661654135338344 15.864661654135338 11.898496240601505 5.275 21.1 15.825000000000001 10.89906102607009 21.8 32.69718307821027    19.55006102607009 56.403999999999996 58.650183078210276
                   Creatine kinase (CK)          2.142857142857143 8.571428571428571 6.428571428571429 2.85 11.4 8.55 5.755215026391282 11.5 17.265645079173844    10.429215026391281 30.195999999999998 31.287645079173842
                   Creatine kinase MB  %          0.6484962406015038 2.593984962406015 1.9454887218045114 0.8625 3.45 2.5875000000000004 6.086421875782191 12.17 18.259265627346572    7.500921875782192 17.828 22.502765627346573
                   Creatine kinase MB  activity          1.8609022556390977 7.443609022556391 5.582706766917293 2.475 9.9 7.425000000000001 3.9102829181531096 7.8 11.730848754459329    7.96928291815311 24.036 23.90784875445933
                   Creatine kinase MB  mass          1.7293233082706765 6.917293233082706 5.1879699248120295 2.3 9.2 6.8999999999999995 7.988272654335229 16.0 23.964817963005686    11.760272654335228 31.087999999999997 35.28081796300569
                   Creatinine (ricos)          0.5075187969924813 2.030075187969925 1.5225563909774438 0.675 2.7 2.0250000000000004 1.8946058297176223 3.8 5.683817489152867    3.0016058297176222 8.228 9.004817489152867
                   Creatinine clearance          1.2781954887218043 5.112781954887217 3.834586466165413 1.7 6.8 5.1 2.395340529027136 4.8 7.186021587081408    5.183340529027136 15.951999999999998 15.550021587081407
                   Cyfra 21 1          2.1240601503759398 8.496240601503759 6.372180451127821 2.825 11.3 8.475000000000001 4.798209301395678 9.6 14.394627904187034    9.431209301395679 28.131999999999998 28.293627904187034
                   Cystastin C          0.4323308270676691 1.7293233082706765 1.2969924812030074 0.575 2.3 1.7249999999999999 1.7237314175938199 3.4 5.17119425278146    2.6667314175938195 7.171999999999999 8.000194252781458
                   Cysteine          0.5639097744360902 2.255639097744361 1.6917293233082706 0.75 3.0 2.25 1.7052309227784959 3.4 5.115692768335488    2.935230922778496 8.32 8.805692768335488
                   Dehydroepiandrosterone sulfate          0.39473684210526316 1.5789473684210527 1.1842105263157896 0.525 2.1 1.5750000000000002 3.699936654863161 7.4 11.099809964589483    4.560936654863161 10.844000000000001 13.682809964589483
                   Dipeptidyl-peptidase IV (ACE)          0.7706766917293232 3.0827067669172927 2.3120300751879697 1.025 4.1 3.0749999999999997 2.082253887017623 4.2 6.246761661052869    3.7632538870176226 10.924 11.289761661052868
                   Dipeptidyl-peptidase IV (ACE)          1.1842105263157894 4.7368421052631575 3.552631578947368 1.575 6.3 4.725 3.7987251150879553 7.6 11.396175345263867    6.381725115087955 17.932 19.145175345263866
                   Elastase          1.2781954887218043 5.112781954887217 3.834586466165413 1.7 6.8 5.1 2.663174797117155 5.3 7.989524391351465    5.4511747971171545 16.451999999999998 16.353524391351463
                   Endotelial growth factor          1.0150375939849625 4.06015037593985 3.0451127819548875 1.35 5.4 4.050000000000001 6.098475731689026 12.2 18.295427195067077    8.312475731689027 21.055999999999997 24.937427195067077
                   Eosinophils  count          1.9736842105263157 7.894736842105263 5.921052631578947 2.625 10.5 7.875 9.904197342541192 19.8 29.712592027623575    14.209197342541191 37.019999999999996 42.62759202762358
                   Epinephrine          2.387218045112782 9.548872180451127 7.1616541353383445 3.175 12.7 9.524999999999999 x x x    x x x
                   Epinephrine          4.548872180451127 18.19548872180451 13.646616541353382 6.05 24.2 18.15 x x x    x x x
                   Erythrocytes  count          0.3007518796992481 1.2030075187969924 0.9022556390977444 0.4 1.6 1.2000000000000002 0.8610495049647261 1.7 2.5831485148941784    1.5170495049647261 4.324 4.551148514894178
                   Erythrocyte distribution wide          0.3383458646616541 1.3533834586466165 1.0150375939849625 0.45 1.8 1.35 0.8360995754095322 1.7 2.5082987262285963    1.5740995754095322 4.652 4.722298726228596
                   Estradiol          1.7105263157894735 6.842105263157894 5.13157894736842 2.275 9.1 6.824999999999999 3.344071246250594 6.7 10.032213738751782    7.075071246250594 21.624 21.22521373875178
                   Factor V coagulation          0.3383458646616541 1.3533834586466165 1.0150375939849625 0.45 1.8 1.35 x x x    x x x
                   Factor VII coagulation          0.6390977443609022 2.5563909774436087 1.9172932330827066 0.85 3.4 2.55 2.5696546460565473 5.1 7.708963938169642    3.963654646056547 10.675999999999998 11.89096393816964
                   Factor VIII coagulation          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 2.4617384609255306 4.9 7.385215382776591    3.4457384609255306 8.836 10.337215382776591
                   Factor X coagulation          0.5639097744360902 2.255639097744361 1.6917293233082706 0.75 3.0 2.25 x x x    x x x
                   Ferritin          1.3345864661654134 5.338345864661654 4.00375939849624 1.775 7.1 5.324999999999999 2.581908209057789 5.2 7.7457246271733675    5.492908209057789 16.843999999999998 16.478724627173367
                   Fibrinogen          1.0150375939849625 4.06015037593985 3.0451127819548875 1.35 5.4 4.050000000000001 2.385273831240346 4.8 7.155821493721039    4.599273831240346 13.655999999999999 13.797821493721038
                   Folate (ricos 1)          1.1278195488721805 4.511278195488722 3.3834586466165413 1.5 6.0 4.5 8.38525491562421 16.8 25.155764746872634    10.84525491562421 26.64 32.53576474687264
                   Folate (ricos 2)          2.255639097744361 9.022556390977444 6.7669172932330826 3.0 12.0 9.0 9.605499726719064 19.2 28.81649918015719    14.525499726719064 38.879999999999995 43.57649918015719
                   Follicle stimulating hormone (males)          0.8270676691729324 3.3082706766917296 2.481203007518797 1.1 4.4 3.3000000000000003 2.4990310622319205 5.0 7.4970931866957615    4.303031062231921 12.216000000000001 12.909093186695761
                   Free carnitine          0.7142857142857142 2.8571428571428568 2.1428571428571423 0.95 3.8 2.8499999999999996 2.1242645786248002 4.2 6.372793735874401    3.6822645786248 10.431999999999999 11.0467937358744
                   Free estradiol          2.142857142857143 8.571428571428571 6.428571428571429 2.85 11.4 8.55 x x x    x x x
                   Free testosterone          0.8834586466165414 3.5338345864661656 2.6503759398496243 1.175 4.7 3.5250000000000004 x x x    x x x
                   Free thyroxine (FT4)          0.5451127819548872 2.180451127819549 1.6353383458646615 0.725 2.9 2.175 1.6719188078372706 3.3 5.015756423511812    2.8609188078372707 8.056 8.58275642351181
                   Free Triiodothyronine (FT3)          0.7518796992481203 3.007518796992481 2.255639097744361 1.0 4.0 3.0 2.411463507913815 4.8 7.234390523741444    4.051463507913815 11.36 12.154390523741444
                   Fructosamine (ricos)          0.3195488721804511 1.2781954887218043 0.9586466165413533 0.425 1.7 1.275 0.851194014311661 1.7 2.553582042934983    1.5481940143116608 4.4879999999999995 4.644582042934983
                   Galactosyl hydroxylisine          1.1090225563909775 4.43609022556391 3.3270676691729326 1.475 5.9 4.425000000000001 3.5463008896595336 7.1 10.6389026689786    5.965300889659534 16.776 17.8959026689786
                   g-Globulins          1.3721804511278195 5.488721804511278 4.116541353383458 1.825 7.3 5.475 2.3863216987656966 4.8 7.15896509629709    5.379321698765697 16.772 16.137965096297087
                   g-glutamyltransferase          1.2969924812030076 5.18796992481203 3.8909774436090228 1.725 6.9 5.175000000000001 5.407517914903288 10.8 16.222553744709863    8.236517914903288 22.116 24.709553744709865
                   Globulins  total          0.5263157894736842 2.1052631578947367 1.5789473684210522 0.7 2.8 2.0999999999999996 1.752943952327056 3.5 5.258831856981168    2.900943952327056 8.091999999999999 8.702831856981167
                   Glucose (ricos)          0.5451127819548872 2.180451127819549 1.6353383458646615 0.725 2.9 2.175 1.1187325417632223 2.2 3.356197625289667    2.3077325417632224 6.9559999999999995 6.923197625289666
                   Glucose-6-phosphate-1-dehydrogenase (G6PDH)          3.0827067669172927 12.330827067669171 9.248120300751879 4.1 16.4 12.299999999999999 5.710571337440764 11.4 17.13171401232229    12.434571337440763 38.296 37.30371401232229
                   Glucose-6-phosphate-1-dehydrogenase (G6PDH)          0.6954887218045113 2.781954887218045 2.086466165413534 0.925 3.7 2.7750000000000004 1.5780724001135056 3.2 4.734217200340517    3.0950724001135055 9.268 9.285217200340517
                   Glutathion peroxidase          0.6766917293233082 2.706766917293233 2.030075187969925 0.9 3.6 2.7 2.8579111690183794 5.7 8.573733507055138    4.333911169018379 11.604 13.001733507055139
                   Glycated albumin          0.48872180451127817 1.9548872180451127 1.4661654135338347 0.65 2.6 1.9500000000000002 1.4422746791093575 2.9 4.326824037328072    2.5082746791093573 7.164 7.524824037328072
                   Glycated total protein          0.09398496240601503 0.37593984962406013 0.2819548872180451 0.125 0.5 0.375 1.454357676089345 2.9 4.363073028268035    1.6593576760893451 3.7199999999999998 4.978073028268035
                   Haptoglobin          1.9172932330827066 7.669172932330826 5.75187969924812 2.55 10.2 7.6499999999999995 5.2158412552530775 10.4 15.647523765759232    9.397841255253077 27.128 28.19352376575923
                   Hematocrit          0.2631578947368421 1.0526315789473684 0.7894736842105261 0.35 1.4 1.0499999999999998 0.873212459828649 1.7 2.619637379485947    1.4472124598286489 3.9959999999999996 4.341637379485947
                   Hemoglobin          0.2631578947368421 1.0526315789473684 0.7894736842105261 0.35 1.4 1.0499999999999998 0.896172416446746 1.8 2.688517249340238    1.4701724164467458 4.096 4.410517249340238
                   Hemoglobin A1 C          0.3195488721804511 1.2781954887218043 0.9586466165413533 0.425 1.7 1.275 0.7661796460360977 1.5 2.298538938108293    1.4631796460360977 4.288 4.389538938108293
                   HDL cholesterol          0.6766917293233082 2.706766917293233 2.030075187969925 0.9 3.6 2.7 2.6175489489214905 5.2 7.852646846764472    4.093548948921491 11.104 12.280646846764473
                   HDL 1 cholesterol          0.5263157894736842 2.1052631578947367 1.5789473684210522 0.7 2.8 2.0999999999999996 3.4688119363839833 6.9 10.40643580915195    4.616811936383983 11.492 13.85043580915195
                   HDL 2 cholesterol          1.4849624060150375 5.93984962406015 4.454887218045113 1.975 7.9 5.925000000000001 5.452894873367724 10.9 16.35868462010317    8.691894873367723 23.856 26.075684620103168
                   HDL 3 cholesterol          0.6578947368421052 2.631578947368421 1.9736842105263157 0.875 3.5 2.625 1.990171160980884 4.0 5.9705134829426525    3.425171160980884 9.739999999999998 10.275513482942653
                   Homocysteine          0.8458646616541353 3.3834586466165413 2.537593984962406 1.125 4.5 3.375 5.161591929821651 10.3 15.484775789464955    7.006591929821651 17.68 21.019775789464955
                   Hydroxyproline/creatinine          2.443609022556391 9.774436090225564 7.330827067669173 3.25 13.0 9.75 5.748382924788501 11.5 17.245148774365504    11.078382924788501 32.82 33.2351487743655
                   Hydroxybutyrate dehydrogenase          0.8270676691729324 3.3082706766917296 2.481203007518797 1.1 4.4 3.3000000000000003 x x x    x x x
                   Immunoglobulin A          0.5075187969924813 2.030075187969925 1.5225563909774438 0.675 2.7 2.0250000000000004 4.537982068056241 9.1 13.613946204168723    5.644982068056241 13.527999999999999 16.934946204168725
                   Immunoglobulin G          0.4323308270676691 1.7293233082706765 1.2969924812030074 0.575 2.3 1.7249999999999999 2.137828922060884 4.3 6.413486766182652    3.080828922060884 8.072 9.242486766182651
                   Immunoglobulin M          0.5639097744360902 2.255639097744361 1.6917293233082706 0.75 3.0 2.25 5.9583187645509526 11.9 17.874956293652858    7.188318764550953 16.82 21.56495629365286
                   Immunoglobulins K chains          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 2.0044092022339153 4.0 6.013227606701745    2.9884092022339153 7.936 8.965227606701745
                   Immunoglobulins l chains          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 2.328626204439004 4.7 6.985878613317011    3.312626204439004 8.636 9.937878613317011
                   Insulin          1.9924812030075185 7.969924812030074 5.977443609022555 2.65 10.6 7.949999999999999 7.750100805796012 15.5 23.250302417388035    12.096100805796011 32.884 36.28830241738803
                   Insulin-like growth factor (IGF-1)          0.8834586466165414 3.5338345864661656 2.6503759398496243 1.175 4.7 3.5250000000000004 3.573688570650778 7.1 10.721065711952335    5.500688570650778 14.808 16.502065711952334
                   Intercellular adhesion molecule-1          0.18796992481203006 0.7518796992481203 0.5639097744360902 0.25 1.0 0.75 2.6357221496204795 5.3 7.907166448861439    3.0457221496204796 6.9399999999999995 9.13716644886144
                   Interferon receptor          1.3157894736842104 5.263157894736842 3.9473684210526314 1.75 7.0 5.25 3.0516389039334255 6.1 9.154916711800276    5.921638903933426 17.58 17.764916711800275
                   Interleukin-1B          2.819548872180451 11.278195488721805 8.458646616541353 3.75 15.0 11.25 5.8576872569299905 11.7 17.57306177078997    12.00768725692999 36.3 36.023061770789965
                   Interleukin-8          2.255639097744361 9.022556390977444 6.7669172932330826 3.0 12.0 9.0 4.900573945978165 9.8 14.701721837934494    9.820573945978165 29.48 29.461721837934494
                   Iron          2.5 10.0 7.500000000000001 3.325 13.3 9.975000000000001 4.402573821073305 8.8 13.207721463219915    9.855573821073305 30.612000000000002 29.566721463219917
                   Lactate (ricos)          2.5563909774436087 10.225563909774435 7.669172932330826 3.4 13.6 10.2 3.989693753911445 8.0 11.969081261734335    9.565693753911445 30.304 28.697081261734333
                   Lactate dehydrogenase (LDH)          0.8082706766917293 3.233082706766917 2.4248120300751874 1.075 4.3 3.2249999999999996 2.128856794150325 4.3 6.386570382450975    3.891856794150325 11.352 11.675570382450974
                   Lactate dehydrogenase 1 isoform (LDH1)          0.6015037593984962 2.406015037593985 1.8045112781954888 0.8 3.2 2.4000000000000004 1.4985930902016062 3.0 4.495779270604819    2.810593090201606 8.248000000000001 8.43177927060482
                   Lactate dehydrogenase 2 isoform (LDH2)          0.4699248120300752 1.8796992481203008 1.4097744360902256 0.625 2.5 1.875 0.8149003006503311 1.6 2.4447009019509935    1.839900300650331 5.699999999999999 5.519700901950993
                   Lactate dehydrogenase 3 isoform (LDH3)          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 0.9125 1.8 2.7375    1.8964999999999999 5.736 5.689499999999999
                   Lactate dehydrogenase 4 isoform (LDH4)          0.8834586466165414 3.5338345864661656 2.6503759398496243 1.175 4.7 3.5250000000000004 1.6267298484997441 3.3 4.880189545499232    3.553729848499744 11.008 10.661189545499234
                   Lactate dehydrogenase 5 isoform (LDH5)          1.1654135338345863 4.661654135338345 3.4962406015037595 1.55 6.2 4.65 2.282131678935289 4.6 6.846395036805867    4.824131678935289 14.767999999999999 14.472395036805867
                   Lactoferrin          1.1090225563909775 4.43609022556391 3.3270676691729326 1.475 5.9 4.425000000000001 3.309385328123638 6.6 9.928155984370914    5.728385328123638 16.276 17.185155984370915
                   Leukocytes  count          1.0338345864661653 4.135338345864661 3.101503759398496 1.375 5.5 4.125 2.8033740831362484 5.6 8.410122249408746    5.058374083136249 14.62 15.175122249408744
                   LDL Cholesterol          0.7894736842105263 3.1578947368421053 2.368421052631579 1.05 4.2 3.1500000000000004 3.37587951503012 6.8 10.12763854509036    5.097879515030121 13.687999999999999 15.29363854509036
                   LDL Cholesterol (direct)          0.6203007518796991 2.4812030075187965 1.8609022556390973 0.825 3.3 2.4749999999999996 x x x    x x x
                   LDL Cholesterol (oxidized)          1.9736842105263157 7.894736842105263 5.921052631578947 2.625 10.5 7.875 6.778873431478124 13.6 20.336620294434372    11.083873431478125 30.82 33.251620294434375
                   LDL receptor mRNA          2.030075187969925 8.1203007518797 6.090225563909775 2.7 10.8 8.100000000000001 3.180040290625262 6.4 9.540120871875786    7.6080402906252615 24.112000000000002 22.824120871875785
                   Leukocytes count          1.0338345864661653 4.135338345864661 3.101503759398496 1.375 5.5 4.125 2.8033740831362484 5.6 8.410122249408746    5.058374083136249 14.62 15.175122249408744
                   Lipase (ricos)          2.180451127819549 8.721804511278195 6.541353383458646 2.9 11.6 8.7 5.04544968263484 10.1 15.13634904790452    9.80144968263484 29.123999999999995 29.404349047904518
                   Lipoprotein (a)          0.8082706766917293 3.233082706766917 2.4248120300751874 1.075 4.3 3.2249999999999996 10.777501159823643 21.6 32.33250347947093    12.540501159823643 28.652 37.62150347947093
                   Lutein          1.8421052631578947 7.368421052631579 5.526315789473684 2.45 9.8 7.3500000000000005 3.582182470226775 7.2 10.746547410680325    7.600182470226775 23.272 22.800547410680323
                   Luteinizing hormone          1.3721804511278195 5.488721804511278 4.116541353383458 1.825 7.3 5.475 3.9192832571785368 7.8 11.75784977153561    6.912283257178537 19.772 20.73684977153561
                   Lycopenene          3.7781954887218046 15.112781954887218 11.334586466165414 5.025 20.1 15.075000000000001 6.491593121106714 --- 19.474779363320142    14.732593121106714  44.19777936332014
                   Lymphocytes  count          0.9774436090225563 3.9097744360902253 2.9323308270676693 1.3 5.2 3.9000000000000004 3.7102055199139574 7.4 11.130616559741872    5.842205519913957 15.928 17.52661655974187
                   Lymphocytes CD4          2.3496240601503757 9.398496240601503 7.048872180451127 3.125 12.5 9.375 x x x    x x x
                   Magnesium (ricos)          0.5263157894736842 2.1052631578947367 1.5789473684210522 0.7 2.8 2.0999999999999996 1.576437835755029 3.2 4.729313507265087    2.7244378357550287 7.792 8.173313507265085
                   Magnesium (ricos2)          1.7293233082706765 6.917293233082706 5.1879699248120295 2.3 9.2 6.8999999999999995 3.0716699448345683 6.1 9.215009834503705    6.843669944834568 21.187999999999995 20.531009834503706
                   Magnesium (ricos3)          0.3383458646616541 1.3533834586466165 1.0150375939849625 0.45 1.8 1.35 0.9178779875342911 1.8 2.753633962602873    1.655877987534291 4.752 4.967633962602873
                   Magnesium  concentration  24h          4.2669172932330826 17.06766917293233 12.800751879699247 5.675 22.7 17.025 7.352635581884907 14.7 22.05790674565472    16.659635581884906 51.928 49.97890674565471
                   Magnesium  ionized          0.18796992481203006 0.7518796992481203 0.5639097744360902 0.25 1.0 0.75 0.6803032412093889 1.4 2.040909723628167    1.090303241209389 3.04 3.270909723628167
                   Magnesium  output  24h          3.6090225563909772 14.436090225563909 10.82706766917293 4.8 19.2 14.399999999999999 6.708960891971275 13.4 20.126882675913826    14.580960891971273 44.888 43.74288267591382
                   Mean corpuscular hemoglobin (HCM)          0.15037593984962405 0.6015037593984962 0.4511278195488722 0.2 0.8 0.6000000000000001 0.6800735254367721 1.4 2.0402205763103165    1.008073525436772 2.7119999999999997 3.0242205763103165
                   Mean corpuscular hemoglobin concentration (MCHC)          0.16917293233082706 0.6766917293233082 0.5075187969924813 0.225 0.9 0.675 0.40945848385398 0.8 1.22837545156194    0.77845848385398 2.276 2.33537545156194
                   Mean corpuscular volume (MCV)          0.13157894736842105 0.5263157894736842 0.39473684210526305 0.175 0.7 0.5249999999999999 0.6216158379578178 1.2 1.8648475138734535    0.9086158379578178 2.348 2.725847513873453
                   Mean platelet volume (MPV)          0.4135338345864662 1.6541353383458648 1.2406015037593985 0.55 2.2 1.6500000000000001 1.1463256518110374 2.3 3.4389769554331124    2.0483256518110373 5.9079999999999995 6.144976955433112
                   Monocytes  count          1.6729323308270676 6.69172932330827 5.018796992481203 2.225 8.9 6.675000000000001 6.610692096898781 13.2 19.832076290696342    10.259692096898782 27.796 30.779076290696345
                   Mucinous carcinoma-associated antigen (MCA)          0.9586466165413533 3.834586466165413 2.87593984962406 1.275 5.1 3.8249999999999997 5.0721358913183705 10.1 15.21640767395511    7.163135891318371 18.464 21.48940767395511
                   Myeloperoxidase          3.3834586466165413 13.533834586466165 10.150375939849624 4.5 18.0 13.5 5.8576872569299905 11.7 17.57306177078997    13.237687256929991 41.22 39.71306177078996
                   Myoglobin          1.3157894736842104 5.263157894736842 3.9473684210526314 1.75 7.0 5.25 4.087652902338945 8.2 12.262958707016836    6.957652902338944 19.68 20.872958707016835
                   N-Acetyl Glucosaminidase  concentration  overnight          4.567669172932331 18.270676691729324 13.703007518796992 6.075 24.3 18.225 6.495815961062936 13.0 19.487447883188807    16.458815961062935 52.852 49.3764478831888
                   Neutrophyles  count          1.5225563909774436 6.090225563909774 4.56766917293233 2.025 8.1 6.074999999999999 4.567292004021639 9.1 13.701876012064918    7.888292004021639 22.384 23.664876012064916
                   Non-inhibited arilestearase activity          0.3571428571428571 1.4285714285714284 1.0714285714285712 0.475 1.9 1.4249999999999998 4.674197792135032 9.3 14.022593376405094    5.453197792135032 12.416 16.359593376405094
                   Norepinephrine          0.9022556390977443 3.6090225563909772 2.7067669172932325 1.2 4.8 3.5999999999999996 x x x    x x x
                   Norepinephrine          1.8421052631578947 7.368421052631579 5.526315789473684 2.45 9.8 7.3500000000000005 x x x    x x x
                   N-terminal (NT)-proBNP          1.9548872180451127 7.819548872180451 5.864661654135339 2.6 10.4 7.800000000000001 5.218776197539037 10.4 15.656328592617111    9.482776197539037 27.456000000000003 28.44832859261711
                   Osmolality          0.13157894736842105 0.5263157894736842 0.39473684210526305 0.175 0.7 0.5249999999999999 0.22114757516192665 0.4 0.66344272548578    0.5081475751619267 1.548 1.5244427254857797
                   Osteocalcin          0.6015037593984962 2.406015037593985 1.8045112781954888 0.8 3.2 2.4000000000000004 2.992960490885237 6.0 8.978881472655711    4.304960490885237 11.248000000000001 12.914881472655711
                   Osteocalcin (+1 trab)          0.6766917293233082 2.706766917293233 2.030075187969925 0.9 3.6 2.7 3.4929393066585055 7.0 10.478817919975516    4.9689393066585055 12.904 14.906817919975516
                   Oxalate  concentration  24h          4.135338345864661 16.541353383458645 12.406015037593985 5.5 22.0 16.5 5.942432162002357 11.9 17.82729648600707    14.962432162002356 47.98 44.887296486007074
                   Oxalate  output  24h          4.003759398496241 16.015037593984964 12.011278195488723 5.325 21.3 15.975000000000001 5.866030386897088 11.7 17.598091160691265    14.599030386897088 46.632000000000005 43.79709116069127
                   pCO2 (ricos)          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 0.8938155570362377 1.8 2.6814466711087133    1.8778155570362376 5.736 5.633446671108713
                   pH [H+]          0.3383458646616541 1.3533834586466165 1.0150375939849625 0.45 1.8 1.35 0.5038911092686593 1.0 1.511673327805978    1.2418911092686593 3.952 3.725673327805978
                   pH (pH units)          0.018796992481203006 0.07518796992481203 0.056390977443609026 0.025 0.1 0.07500000000000001 x x x    x x x
                   Paraoxon          1.2593984962406015 5.037593984962406 3.7781954887218046 1.675 6.7 5.025 10.63276187074647 21.3 31.898285612239413    13.37976187074647 32.288 40.13928561223941
                   Paraoxonase 1 substrate inhibition (PON 4SI)          0.3571428571428571 1.4285714285714284 1.0714285714285712 0.475 1.9 1.4249999999999998 10.024360952200395 20.0 30.073082856601182    10.803360952200395 23.116 32.41008285660118
                   Paraoxonase activity (salt estimulated)          0.7518796992481203 3.007518796992481 2.255639097744361 1.0 4.0 3.0 10.846197490365 21.7 32.538592471095    12.486197490365 28.259999999999998 37.458592471095
                   Parathyroid hormone (PTH)          2.443609022556391 9.774436090225564 7.330827067669173 3.25 13.0 9.75 4.396820584240389 8.8 13.190461752721168    9.72682058424039 30.12 29.180461752721165
                   Phenylacetate          0.6203007518796991 2.4812030075187965 1.8609022556390973 0.825 3.3 2.4749999999999996 3.256244001913861 6.5 9.768732005741583    4.609244001913861 11.911999999999999 13.827732005741582
                   Phosphate (ricos)          0.8082706766917293 3.233082706766917 2.4248120300751874 1.075 4.3 3.2249999999999996 1.5841500086797335 3.2 4.752450026039201    3.3471500086797334 10.251999999999999 10.0414500260392
                   Phosphate tubular reabsorption          0.2631578947368421 1.0526315789473684 0.7894736842105261 0.35 1.4 1.0499999999999998 0.532975140133196 1.1 1.598925420399588    1.106975140133196 3.396 3.3209254203995875
                   Phospholipids          0.6203007518796991 2.4812030075187965 1.8609022556390973 0.825 3.3 2.4749999999999996 1.6078906990215471 3.2 4.823672097064641    2.960890699021547 8.611999999999998 8.88267209706464
                   Plasminogen          0.7330827067669172 2.932330827067669 2.1992481203007515 0.975 3.9 2.925 x x x    x x x
                   Platelets  count          0.8646616541353382 3.458646616541353 2.5939849624060147 1.15 4.6 3.4499999999999997 2.9644244804008753 5.9 8.893273441202625    4.850424480400875 13.443999999999999 14.551273441202625
                   Platelet distribution wide          0.2631578947368421 1.0526315789473684 0.7894736842105261 0.35 1.4 1.0499999999999998 x x x    x x x
                   Plateletcrit          1.1278195488721805 4.511278195488722 3.3834586466165413 1.5 6.0 4.5 x x x    x x x
                   Potassium (ricos)          1.2781954887218043 5.112781954887217 3.834586466165413 1.7 6.8 5.1 2.3865508584566135 4.8 7.15965257536984    5.174550858456613 15.951999999999998 15.52365257536984
                   Potassium (ricos2)          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 0.9219544457292886 1.8 2.765863337187866    1.9059544457292885 5.736 5.7178633371878655
                   Prealbumin          1.0338345864661653 4.135338345864661 3.101503759398496 1.375 5.5 4.125 2.74892024256798 5.5 8.24676072770394    5.00392024256798 14.52 15.01176072770394
                   Procollagen type 1 C-terminal          0.7330827067669172 2.932330827067669 2.1992481203007515 0.975 3.9 2.925 x x x    x x x
                   Procollagen type 1 N-terminal          0.6390977443609022 2.5563909774436087 1.9172932330827066 0.85 3.4 2.55 2.4520399670478454 4.9 7.356119901143536    3.8460399670478456 10.475999999999999 11.538119901143535
                   Prolactin (men)          0.6578947368421052 2.631578947368421 1.9736842105263157 0.875 3.5 2.625 7.698467785864926 15.4 23.095403357594776    9.133467785864926 21.14 27.400403357594776
                   Prolyl endopeptidase          1.5789473684210527 6.315789473684211 4.736842105263158 2.1 8.4 6.300000000000001 2.7256019977245396 5.5 8.17680599317362    6.1696019977245395 19.276 18.50880599317362
                   Properdin factor B          0.8834586466165414 3.5338345864661656 2.6503759398496243 1.175 4.7 3.5250000000000004 1.8357985319745738 3.7 5.507395595923722    3.762798531974574 11.408000000000001 11.288395595923722
                   Prostatic specific antigen (PSA)          1.7105263157894735 6.842105263157894 5.13157894736842 2.275 9.1 6.824999999999999 9.328526477959958 18.7 27.985579433879874    13.059526477959958 33.623999999999995 39.178579433879875
                   Protein C          0.5451127819548872 2.180451127819549 1.6353383458646615 0.725 2.9 2.175 6.937984217335753 13.9 20.81395265200726    8.126984217335753 18.656 24.38095265200726
                   Protein S          0.5451127819548872 2.180451127819549 1.6353383458646615 0.725 2.9 2.175 7.958093364619442 15.9 23.874280093858324    9.147093364619442 20.656 27.441280093858325
                   Protein  total          0.2631578947368421 1.0526315789473684 0.7894736842105261 0.35 1.4 1.0499999999999998 0.6032464256006826 1.2 1.809739276802048    1.1772464256006825 3.4959999999999996 3.5317392768020475
                   Prothrombin time          0.37593984962406013 1.5037593984962405 1.1278195488721805 0.5 2.0 1.5 0.986154146165801 2.0 2.9584624384974028    1.806154146165801 5.279999999999999 5.418462438497403
                   Pyruvate          1.4285714285714284 5.7142857142857135 4.285714285714285 1.9 7.6 5.699999999999999 2.500124996875156 5.0 7.500374990625469    5.616124996875156 17.464 16.848374990625466
                   Red cell distribution wide (RDW)          0.3383458646616541 1.3533834586466165 1.0150375939849625 0.45 1.8 1.35 0.8360995754095322 1.7 2.5082987262285963    1.5740995754095322 4.652 4.722298726228596
                   Reticulocyte highly fluorescent  count          0.9398496240601504 3.7593984962406015 2.819548872180451 1.25 5.0 3.75 7.850159234053791 15.7 23.550477702161373    9.900159234053792 23.9 29.700477702161372
                   Reticulocyte low fluorescent  count          0.15037593984962405 0.6015037593984962 0.4511278195488722 0.2 0.8 0.6000000000000001 0.6443261984429938 1.3 1.9329785953289813    0.9723261984429938 2.612 2.9169785953289815
                   Reticulocyte medium fluorescent  count          1.2218045112781954 4.887218045112782 3.6654135338345863 1.625 6.5 4.875 4.43353696274205 8.9 13.30061088822615    7.09853696274205 19.560000000000002 21.29561088822615
                   Reticulocyte  count          1.0338345864661653 4.135338345864661 3.101503759398496 1.375 5.5 4.125 3.877015604817706 7.8 11.631046814453118    6.132015604817706 16.82 18.39604681445312
                   Retinol          0.5827067669172932 2.3308270676691727 1.7481203007518797 0.775 3.1 2.325 2.737014797183238 5.5 8.211044391549713    4.008014797183238 10.584 12.024044391549713
                   Retinol          1.2781954887218043 5.112781954887217 3.834586466165413 1.7 6.8 5.1 2.9207233693042554 5.8 8.762170107912766    5.708723369304256 16.951999999999998 17.126170107912763
                   Rheumatoid factor          0.8082706766917293 3.233082706766917 2.4248120300751874 1.075 4.3 3.2249999999999996 3.241575619972485 6.5 9.724726859917455    5.004575619972485 13.552 15.013726859917455
                   SCC antigen          3.703007518796992 14.812030075187968 11.109022556390975 4.925 19.7 14.774999999999999 6.64601619393152 13.3 19.93804858179456    14.723016193931521 45.608000000000004 44.169048581794556
                   Selenium          1.1278195488721805 4.511278195488722 3.3834586466165413 1.5 6.0 4.5 2.3048861143232218 4.6 6.914658342969665    4.764886114323222 14.44 14.294658342969665
                   Selenium          1.1278195488721805 4.511278195488722 3.3834586466165413 1.5 6.0 4.5 2.1213203435596424 4.2 6.363961030678928    4.581320343559643 14.04 13.743961030678928
                   Semen  concentration          2.518796992481203 10.075187969924812 7.556390977443609 3.35 13.4 10.05 7.80544681616626 15.6 23.41634044849878    13.29944681616626 37.576 39.89834044849878
                   Semen  morphology          1.8421052631578947 7.368421052631579 5.526315789473684 2.45 9.8 7.3500000000000005 6.021004899516359 12.0 18.063014698549075    10.039004899516359 28.072 30.117014698549077
                   Semen  progressive motility          1.4285714285714284 5.7142857142857135 4.285714285714285 1.9 7.6 5.699999999999999 4.518849411078001 9.0 13.556548233234004    7.634849411078001 21.464 22.904548233234003
                   Semen  progressive rapid motility          1.7669172932330828 7.067669172932331 5.3007518796992485 2.35 9.4 7.050000000000001 6.888259939926773 13.8 20.66477981978032    10.742259939926774 29.216 32.22677981978032
                   Semen  total motility          1.7293233082706765 6.917293233082706 5.1879699248120295 2.3 9.2 6.8999999999999995 4.377856210521309 8.8 13.133568631563929    8.149856210521309 23.887999999999998 24.449568631563928
                   Semen  vitality          0.9774436090225563 3.9097744360902253 2.9323308270676693 1.3 5.2 3.9000000000000004 3.472503599710157 6.9 10.417510799130472    5.604503599710157 15.428 16.813510799130473
                   Sex hormone binding globulin (SHBG)          1.1466165413533833 4.586466165413533 3.4398496240601495 1.525 6.1 4.574999999999999 5.547662796169212 11.1 16.642988388507636    8.048662796169213 21.104 24.145988388507632
                   Sodium (ricos)          0.16917293233082706 0.6766917293233082 0.5075187969924813 0.225 0.9 0.675 1.5662455107677087 3.1 4.698736532303126    1.9352455107677087 4.5760000000000005 5.8057365323031265
                   Sodium (ricos2)          4.793233082706767 19.172932330827066 14.3796992481203 6.375 25.5 19.125 7.832185199546803 15.7 23.49655559864041    18.287185199546805 57.519999999999996 54.86155559864041
                   Sodium (ricos3)          0.07518796992481203 0.3007518796992481 0.2255639097744361 0.1 0.4 0.30000000000000004 0.1525819451966713 0.3 0.45774583559001386    0.31658194519667127 0.956 0.9497458355900139
                   Sodium Bicarbonate          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 0.8397358215534216 1.7 2.5192074646602647    1.8237358215534214 5.635999999999999 5.471207464660264
                   Sodium Chloride          1.4097744360902256 5.639097744360902 4.2293233082706765 1.875 7.5 5.625 3.6443449342783127 7.3 10.93303480283494    6.719344934278313 19.599999999999998 20.15803480283494
                   Soluble CD163          0.8458646616541353 3.3834586466165413 2.537593984962406 1.125 4.5 3.375 4.6263680409150325 9.3 13.879104122745098    6.471368040915032 16.68 19.414104122745098
                   Soluble CD163          0.4323308270676691 1.7293233082706765 1.2969924812030074 0.575 2.3 1.7249999999999999 0.795495128834866 1.6 2.3864853865045976    1.7384951288348658 5.372 5.215485386504597
                   Superoxide dismutase          1.6165413533834585 6.466165413533834 4.849624060150375 2.15 8.6 6.449999999999999 2.5082987262285967 5.0 7.52489617868579    6.034298726228597 19.104 18.10289617868579
                   Superoxide dismutase          1.1654135338345863 4.661654135338345 3.4962406015037595 1.55 6.2 4.65 1.6550113292663589 3.3 4.965033987799076    4.197011329266359 13.468 12.591033987799076
                   Testosterone (ricos)          0.8834586466165414 3.5338345864661656 2.6503759398496243 1.175 4.7 3.5250000000000004 3.1824224263915686 6.4 9.547267279174706    5.109422426391569 14.108 15.328267279174707
                   Testosterone (ricos2)          1.6353383458646615 6.541353383458646 4.906015037593984 2.175 8.7 6.5249999999999995 4.199572150826796 8.4 12.598716452480389    7.7665721508267955 22.668 23.29971645248039
                   Testosterone (ricos3)          2.3496240601503757 9.398496240601503 7.048872180451127 3.125 12.5 9.375 x x x    x x x
                   Thyroglobulin          1.3157894736842104 5.263157894736842 3.9473684210526314 1.75 7.0 5.25 5.179587338775165 10.4 15.538762016325496    8.049587338775165 21.88 24.148762016325495
                   Thyroglobulin antibody          0.8082706766917293 3.233082706766917 2.4248120300751874 1.075 4.3 3.2249999999999996 10.304921457730767 20.6 30.914764373192302    12.067921457730767 27.652 36.2037643731923
                   Thyroid peroxidase antibody          1.0714285714285714 4.285714285714286 3.2142857142857144 1.425 5.7 4.275 18.42921000070269 36.9 55.28763000210807    20.76621000070269 46.248 62.29863000210807
                   Thyroid stimulating hormone (TSH)          1.8233082706766914 7.293233082706766 5.469924812030074 2.425 9.7 7.2749999999999995 3.9084243948169193 7.8 11.725273184450758    7.885424394816919 23.708 23.656273184450757
                   Thyrotropin receptor antibody          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 x x x    x x x
                   Thyroxine binding globulin (TBG)          0.4135338345864662 1.6541353383458648 1.2406015037593985 0.55 2.2 1.6500000000000001 1.6682700620702873 3.3 5.004810186210862    2.5702700620702874 6.9079999999999995 7.710810186210862
                   Thyroxine (T4)          0.4699248120300752 1.8796992481203008 1.4097744360902256 0.625 2.5 1.875 1.4938415243927314 3.0 4.481524573178194    2.518841524392731 7.1 7.556524573178194
                   Tissue polypeptide antigen (TPA)          2.706766917293233 10.827067669172932 8.1203007518797 3.6 14.4 10.8 6.194566671688989 12.4 18.583700015066967    12.098566671688989 36.016 36.29570001506697
                   Tissue polypeptide specific antigen (TPS)          3.4022556390977443 13.609022556390977 10.206766917293233 4.525 18.1 13.575000000000001 14.234207257518769 28.5 42.702621772556306    21.655207257518768 58.184 64.9656217725563
                   Total carnitine          0.7330827067669172 2.932330827067669 2.1992481203007515 0.975 3.9 2.925 1.9753559805766656 4.0 5.926067941729997    3.574355980576666 10.396 10.723067941729997
                   Transferrin          0.2819548872180451 1.1278195488721805 0.8458646616541353 0.375 1.5 1.125 0.6553863364459165 1.3 1.9661590093377495    1.2703863364459165 3.76 3.811159009337749
                   Triglyceride          1.9736842105263157 7.894736842105263 5.921052631578947 2.625 10.5 7.875 5.333634431604776 10.7 16.00090329481433    9.638634431604775 27.919999999999998 28.915903294814328
                   Triiodothyronine (T3)          0.8270676691729324 3.3082706766917296 2.481203007518797 1.1 4.4 3.3000000000000003 2.4093891860801566 4.8 7.22816755824047    4.213389186080157 12.016 12.64016755824047
                   Troponin I          1.3157894736842104 5.263157894736842 3.9473684210526314 1.75 7.0 5.25 8.067101400131277 16.1 24.201304200393828    10.937101400131276 27.58 32.81130420039383
                   Tumor Necrosis Factor-a          4.041353383458646 16.165413533834585 12.12406015037594 5.375 21.5 16.125 6.48315123994497 13.0 19.44945371983491    15.29815123994497 48.26 45.89445371983491
                   Urate          0.8458646616541353 3.3834586466165413 2.537593984962406 1.125 4.5 3.375 2.470956292612235 4.9 7.412868877836705    4.315956292612235 12.280000000000001 12.947868877836704
                   Urea          1.1654135338345863 4.661654135338345 3.4962406015037595 1.55 6.2 4.65 2.756186223751944 5.5 8.268558671255832    5.298186223751944 15.668 15.894558671255833
                   Vascular cell adhesion molecule-1          0.48872180451127817 1.9548872180451127 1.4661654135338347 0.65 2.6 1.9500000000000002 2.102974084481309 4.2 6.308922253443928    3.1689740844813095 8.464 9.506922253443928
                   Vascular endotelial growth factor          1.3345864661654134 5.338345864661654 4.00375939849624 1.775 7.1 5.324999999999999 4.008292186205991 8.0 12.024876558617972    6.919292186205991 19.644 20.757876558617973
                   Vitamin B1          0.45112781954887216 1.8045112781954886 1.3533834586466162 0.6 2.4 1.7999999999999998 1.6155494421403511 3.2 4.846648326421054    2.599549442140351 7.135999999999999 7.798648326421054
                   Vitamin B2 (Riboflavin)          0.5451127819548872 2.180451127819549 1.6353383458646615 0.725 2.9 2.175 1.4450346016618425 2.9 4.335103804985527    2.6340346016618423 7.655999999999999 7.902103804985527
                   Vitamin B2 (Riboflavin)          0.6015037593984962 2.406015037593985 1.8045112781954888 0.8 3.2 2.4000000000000004 1.5907938269933033 3.2 4.772381480979909    2.902793826993303 8.448 8.70838148097991
                   Vitamin B2 status (gluthation reductase activation)          0.48872180451127817 1.9548872180451127 1.4661654135338347 0.65 2.6 1.9500000000000002 5.042072986381693 10.1 15.126218959145078    6.108072986381693 14.364 18.324218959145078
                   Vitamin B12          1.4097744360902256 5.639097744360902 4.2293233082706765 1.875 7.5 5.625 8.826451721954864 17.7 26.479355165864593    11.901451721954864 30.0 35.70435516586459
                   Vitamin B6          1.3157894736842104 5.263157894736842 3.9473684210526314 1.75 7.0 5.25 3.473110997362451 6.9 10.419332992087353    6.343110997362451 18.38 19.029332992087355
                   Vitamin B6          1.8796992481203008 7.518796992481203 5.639097744360902 2.5 10.0 7.5 4.930770730829005 9.9 14.792312192487016    9.030770730829005 26.299999999999997 27.092312192487014
                   Vitamin B6 status (AST activation)          0.13157894736842105 0.5263157894736842 0.39473684210526305 0.175 0.7 0.5249999999999999 5.502783386614451 11.0 16.508350159843353    5.789783386614451 12.148 17.369350159843354
                   Vitamin E (a-Tocopherol)          0.7142857142857142 2.8571428571428568 2.1428571428571423 0.95 3.8 2.8499999999999996 2.791616914979561 5.6 8.374850744938684    4.349616914979561 11.831999999999999 13.048850744938683
                   Vitamin K (Phylloquinone)          3.571428571428571 14.285714285714285 10.714285714285714 4.75 19.0 14.25 7.267220926874317 14.5 21.80166278062295    15.057220926874315 45.66 45.17166278062295
                   VLDL Cholesterol          2.593984962406015 10.37593984962406 7.7819548872180455 3.45 13.8 10.350000000000001 x x x    x x x
                   Von Willebrand factor          9.398496240601503e-05 0.0003759398496240601 0.00028195488721804513 0.000125 0.0005 0.000375 3.5375000022084806 7.1 10.612500006625442    3.5377050022084804 7.10082 10.613115006625442
                   Von Willebrand factor antigen          0.4699248120300752 1.8796992481203008 1.4097744360902256 0.625 2.5 1.875 2.3351927115336757 4.7 7.005578134601027    3.3601927115336756 8.8 10.080578134601026
                   Water          0.3007518796992481 1.2030075187969924 0.9022556390977444 0.4 1.6 1.2000000000000002 0.38770156048177057 0.8 1.1631046814453117    1.0437015604817705 3.4240000000000004 3.131104681445312
                   Zeaxanthine          3.270676691729323 13.082706766917292 9.812030075187968 4.35 17.4 13.049999999999999 x x x    x x x
                   Zinc (ricos 1)          0.8834586466165414 3.5338345864661656 2.6503759398496243 1.175 4.7 3.5250000000000004 1.652885734102633 3.3 4.958657202307899    3.579885734102633 11.008 10.7396572023079
                   Zinc (ricos 2)          1.0338345864661653 4.135338345864661 3.101503759398496 1.375 5.5 4.125 2.225561726845607 4.5 6.676685180536822    4.4805617268456075 13.52 13.441685180536822
                   URINE                        
                   4 OH-3 methoxi-Vanil mandelic acid (VMA)          2.0864661654135337 8.345864661654135 6.259398496240601 2.775 11.1 8.325 6.497403327483989 13.0 19.492209982451968    11.048403327483989 31.203999999999997 33.145209982451966
                   5'-Hydroxyindolacetate  concentration          1.9172932330827066 7.669172932330826 5.75187969924812 2.55 10.2 7.6499999999999995 4.864299153012693 9.7 14.59289745903808    9.046299153012693 26.427999999999997 27.138897459038077
                   a1-Microglobulin  concentration  first morning          3.101503759398496 12.406015037593985 9.304511278195488 4.125 16.5 12.375 8.341350310351435 16.7 25.024050931054305    15.106350310351434 43.76 45.319050931054306
                   a2-Microglobulin output  first morning          2.725563909774436 10.902255639097744 8.176691729323307 3.625 14.5 10.875 5.398205720422296 10.8 16.194617161266887    11.343205720422295 34.58 34.029617161266884
                   a-Amylase concentration  random          8.834586466165414 35.338345864661655 26.50375939849624 11.75 47.0 35.25 13.08147545195113 26.2 39.24442635585339    32.35147545195113 103.28 97.0544263558534
                   Albumin  concentration  first morning          3.3834586466165413 13.533834586466165 10.150375939849624 4.5 18.0 13.5 8.216789214772398 16.4 24.650367644317193    15.596789214772397 45.92 46.790367644317186
                   Aldosterone  concentration          3.06390977443609 12.25563909774436 9.191729323308271 4.075 16.3 12.225000000000001 6.353837423164053 12.7 19.06151226949216    13.036837423164052 39.432 39.11051226949216
                   Ammonia  output  24h          2.3308270676691727 9.32330827067669 6.992481203007519 3.1 12.4 9.3 4.601935734014546 9.2 13.805807202043638    9.685935734014546 29.535999999999998 29.05780720204364
                   Calcium  concentration  24h          2.593984962406015 10.37593984962406 7.7819548872180455 3.45 13.8 10.350000000000001 5.722502184359566 11.4 17.1675065530787    11.380502184359568 34.032000000000004 34.1415065530787
                   Calcium  ionized          0.16917293233082706 0.6766917293233082 0.5075187969924813 0.225 0.9 0.675 0.31868871959954903 0.6 0.9560661587986471    0.687688719599549 2.076 2.063066158798647
                   Calcium  output  24h          2.462406015037594 9.849624060150376 7.387218045112781 3.275 13.1 9.825 4.70279172407199 9.4 14.108375172215972    10.07379172407199 30.884 30.22137517221597
                   C-Terminal cross-linking telopeptide  type I collagen (s-CTx)          0.9022556390977443 3.6090225563909772 2.7067669172932325 1.2 4.8 3.5999999999999996 4.0088184044678306 8.0 12.02645521340349    5.9768184044678305 15.872 17.93045521340349
                   C-Telopeptide of type I collagen/creatinine  1st morning          3.0827067669172927 12.330827067669171 9.248120300751879 4.1 16.4 12.299999999999999 7.267048919609665 14.5 21.801146758828995    13.991048919609664 41.396 41.97314675882899
                   C-Telopeptide type I collagen/creatinine  2nd morning          2.1992481203007515 8.796992481203006 6.597744360902254 2.925 11.7 8.774999999999999 x x x    x x x
                   Creatinine  concentration  24h          2.255639097744361 9.022556390977444 6.7669172932330826 3.0 12.0 9.0 4.287062659910629 8.6 12.861187979731888    9.20706265991063 28.28 27.621187979731886
                   Creatinine  output  24h          1.0338345864661653 4.135338345864661 3.101503759398496 1.375 5.5 4.125 3.1868871959954905 6.4 9.560661587986472    5.44188719599549 15.42 16.32566158798647
                   ?-aminolevulinic acid          1.5037593984962405 6.015037593984962 4.511278195488722 2.0 8.0 6.0 3.923088706618804 7.8 11.769266119856411    7.203088706618804 20.919999999999998 21.60926611985641
                   Deoxypyridinoline/creatinine  24h (Delmas CC 2001)          1.2781954887218043 5.112781954887217 3.834586466165413 1.7 6.8 5.1 2.7726623036352627 5.5 8.317986910905788    5.5606623036352625 16.652 16.681986910905785
                   Deoxypyridinoline/creatinine  first morning          1.2406015037593983 4.962406015037593 3.7218045112781946 1.65 6.6 4.949999999999999 2.8847931034997987 5.8 8.654379310499396    5.590793103499799 16.624 16.772379310499396
                   Deoxipyridinoline/minute          2.5 10.0 7.500000000000001 3.325 13.3 9.975000000000001 5.557568038269977 11.1 16.67270411480993    11.010568038269977 32.912 33.03170411480993
                   Estradiol          2.8571428571428568 11.428571428571427 8.57142857142857 3.8 15.2 11.399999999999999 x x x    x x x
                   Free estradiol          3.6278195488721803 14.511278195488721 10.883458646616543 4.825 19.3 14.475000000000001 x x x    x x x
                   Free testosterone          4.868421052631579 19.473684210526315 14.605263157894735 6.475 25.9 19.424999999999997 x x x    x x x
                   Hydroxyproline/minute  night urine          3.4022556390977443 13.609022556390977 10.206766917293233 4.525 18.1 13.575000000000001 6.624587251293471 13.2 19.873761753880416    14.045587251293473 42.884 42.13676175388042
                   Magnesium  concentration  24h          4.2669172932330826 17.06766917293233 12.800751879699247 5.675 22.7 17.025 7.352635581884907 14.7 22.05790674565472    16.659635581884906 51.928 49.97890674565471
                   Magnesium  ionized          0.18796992481203006 0.7518796992481203 0.5639097744360902 0.25 1.0 0.75 0.6803032412093889 1.4 2.040909723628167    1.090303241209389 3.04 3.270909723628167
                   Magnesium  output  24h          3.6090225563909772 14.436090225563909 10.82706766917293 4.8 19.2 14.399999999999999 6.708960891971275 13.4 20.126882675913826    14.580960891971273 44.888 43.74288267591382
                   N-Acetyl Glucosaminidase  concentration  overnight          4.567669172932331 18.270676691729324 13.703007518796992 6.075 24.3 18.225 6.495815961062936 13.0 19.487447883188807    16.458815961062935 52.852 49.3764478831888
                   Nitrogen  output          1.3157894736842104 5.263157894736842 3.9473684210526314 1.75 7.0 5.25 3.4884855238340893 7.0 10.465456571502267    6.358485523834089 18.479999999999997 19.075456571502265
                   N- Telopeptide of type I collagen /creatinine  first urine          1.6165413533834585 6.466165413533834 4.849624060150375 2.15 8.6 6.449999999999999 5.998541489395568 12.0 17.995624468186705    9.524541489395567 26.104 28.5736244681867
                   Oxalate  concentration  24h          4.135338345864661 16.541353383458645 12.406015037593985 5.5 22.0 16.5 5.942432162002357 11.9 17.82729648600707    14.962432162002356 47.98 44.887296486007074
                   Oxalate  output  24h          4.003759398496241 16.015037593984964 12.011278195488723 5.325 21.3 15.975000000000001 5.866030386897088 11.7 17.598091160691265    14.599030386897088 46.632000000000005 43.79709116069127
                   Phosphate  concentration  24h          2.4812030075187965 9.924812030075186 7.443609022556389 3.3 13.2 9.899999999999999 4.675751944874749 9.4 14.027255834624247    10.087751944874748 31.047999999999995 30.263255834624246
                   Phosphate  output  24h          1.6917293233082706 6.7669172932330826 5.075187969924812 2.25 9.0 6.75 3.611526685489116 7.2 10.834580056467349    7.301526685489116 21.96 21.904580056467346
                   Porphobilinogen          1.5977443609022555 6.390977443609022 4.793233082706767 2.125 8.5 6.375 4.419417382415922 8.8 13.258252147247767    7.904417382415922 22.740000000000002 23.713252147247765
                   Porphyrins          3.7593984962406015 15.037593984962406 11.278195488721805 5.0 20.0 15.0 x x x    x x x
                   Potassium  concentration  24h          2.5563909774436087 10.225563909774435 7.669172932330826 3.4 13.6 10.2 4.459277547989136 8.9 13.377832643967409    10.035277547989136 31.204 30.105832643967407
Validation analytique LABM (XLS) - Fichier XLS

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